38hm: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "38hm": Seeded page ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite)) |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM Structure of GTP Cyclohydrolase I from Candida albicans bound to 7-Deaza GTP and BH2 at 1.96 A== | |||
<StructureSection load='38hm' size='340' side='right'caption='[[38hm]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[38hm]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=38HM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=38HM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HBI:7,8-DIHYDROBIOPTERIN'>HBI</scene>, <scene name='pdbligand=QBQ:[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-4-oxidanylidene-3~{H}-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>QBQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=38hm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=38hm OCA], [https://pdbe.org/38hm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=38hm RCSB], [https://www.ebi.ac.uk/pdbsum/38hm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=38hm ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/C4YRY1_CANAW C4YRY1_CANAW] GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.[ARBA:ARBA00055676] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Candida albicans]] | ||
[[Category: Large Structures]] | |||
[[Category: Borek D]] | |||
[[Category: Guo Y]] | |||
[[Category: Klose T]] | |||
[[Category: Mesecar AD]] | |||
[[Category: Oluwarotimi EA]] | |||
[[Category: Vago F]] | |||