9xqf: Difference between revisions
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==Cryo-EM structure of human SLC26A11== | |||
<StructureSection load='9xqf' size='340' side='right'caption='[[9xqf]], [[Resolution|resolution]] 3.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9xqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9XQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9XQF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.82Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9xqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9xqf OCA], [https://pdbe.org/9xqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9xqf RCSB], [https://www.ebi.ac.uk/pdbsum/9xqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9xqf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/S2611_HUMAN S2611_HUMAN] Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport (By similarity). Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) (PubMed:12626430). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion (By similarity). May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum (By similarity).[UniProtKB:G3C7W6][UniProtKB:Q80ZD3]<ref>PMID:12626430</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chi X]] | |||
[[Category: Wang A]] | |||
[[Category: Wang Y]] | |||
[[Category: Wu S]] | |||
[[Category: Yan R]] | |||