1z4u: Difference between revisions

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[[Image:1z4u.gif|left|200px]]
{{Seed}}
[[Image:1z4u.png|left|200px]]


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{{STRUCTURE_1z4u|  PDB=1z4u  |  SCENE=  }}  
{{STRUCTURE_1z4u|  PDB=1z4u  |  SCENE=  }}  


'''hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585'''
===hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585===




==Overview==
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A novel series of non-nucleoside HCV NS5B polymerase inhibitors was prepared from a (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid template. Solution and solid phase analog synthesis focused on the northern region of the template combined with structure based design led to the discovery of several potent and orally bioavailable lead compounds.
The line below this paragraph, {{ABSTRACT_PUBMED_15911260}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15911260 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15911260}}


==About this Structure==
==About this Structure==
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[[Category: Polymerase]]
[[Category: Polymerase]]
[[Category: Thumb]]
[[Category: Thumb]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 17:10:43 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:11:18 2008''