1zxc: Difference between revisions

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-[[Image:1zxc.gif|left|200px]]
+{{Seed}}
+[[Image:1zxc.png|left|200px]]
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 {{STRUCTURE_1zxc|  PDB=1zxc  |  SCENE=  }}
-'''Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor'''
+===Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor===
-==Overview==
+<!--
-The SAR of a series of potent sulfonamide hydroxamate TACE inhibitors bearing a butynyloxy P1' group was explored. In particular, compound 5k has excellent in vitro potency against TACE enzyme and in cells, and oral activity in an in vivo model of TNF-alpha production and a collagen-induced arthritis model.
+The line below this paragraph, {{ABSTRACT_PUBMED_16084720}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16084720 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16084720}}
 ==About this Structure==
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 [[Category: Tace/adam-17]]
 [[Category: Zn-endopeptidase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:11:47 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:29:18 2008''

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