|
|
| Line 1: |
Line 1: |
| [[Image:243d.gif|left|200px]] | | {{Seed}} |
| | [[Image:243d.png|left|200px]] |
|
| |
|
| <!-- | | <!-- |
| Line 9: |
Line 10: |
| {{STRUCTURE_243d| PDB=243d | SCENE= }} | | {{STRUCTURE_243d| PDB=243d | SCENE= }} |
|
| |
|
| '''STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2'''
| | ===STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2=== |
|
| |
|
|
| |
|
| ==Overview==
| | <!-- |
| d(ACGTACGT), C(78)H(84)N(30)O(32)P(7).20H(2)O, M(r) (DNA) = 2170, tetragonal, P4(3)2(1)2 (No 96), a = 42.845 (1), b = 42.845(1), c = 24.804 (1) A, V = 45532.5 (2) A(3), z = 8,lambda(MoKalpha) = 0.71069 A, micro (MoKalpha) = 0.10 mm(-1), T = 295 K, R = 0.18 for 1994 unique reflections between 5.0 and 1.9 A resolution. The self-complementary octanucleotide d(ACGTACGT)(2) has been crystallized and its structure determined to a resolution of 1.9 A. The asymmetric unit consists of a single strand of octamer with 20 water molecules. It is only the second example of an octanucleotide having terminal A.T base pairs whose structure has been determined by X-ray crystallography. The sequence adopts the modified A-type conformation found for all octanucleotide duplexes studied to date with the helix bent by approximately 15 degrees and an average tilt angle of 0 degrees. Unusually the data collection was carried out using a 3 kW molybdenum sealed-tube source. The conformational details are discussed in comparison with other closely related sequences.
| | The line below this paragraph, {{ABSTRACT_PUBMED_15299669}}, adds the Publication Abstract to the page |
| | (as it appears on PubMed at http://www.pubmed.gov), where 15299669 is the PubMed ID number. |
| | --> |
| | {{ABSTRACT_PUBMED_15299669}} |
|
| |
|
| ==About this Structure== | | ==About this Structure== |
| Line 26: |
Line 30: |
| [[Category: A-dna]] | | [[Category: A-dna]] |
| [[Category: Double helix]] | | [[Category: Double helix]] |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:22:15 2008'' | | |
| | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:49:12 2008'' |
