2ahm: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:2ahm.gif|left|200px]]
{{Seed}}
[[Image:2ahm.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ahm|  PDB=2ahm  |  SCENE=  }}  
{{STRUCTURE_2ahm|  PDB=2ahm  |  SCENE=  }}  


'''Crystal structure of SARS-CoV super complex of non-structural proteins: the hexadecamer'''
===Crystal structure of SARS-CoV super complex of non-structural proteins: the hexadecamer===




==Overview==
<!--
Coronavirus replication and transcription machinery involves multiple virus-encoded nonstructural proteins (nsp). We report the crystal structure of the hexadecameric nsp7-nsp8 supercomplex from the severe acute respiratory syndrome coronavirus at 2.4-angstroms resolution. nsp8 has a novel 'golf-club' fold with two conformations. The supercomplex is a unique hollow, cylinder-like structure assembled from eight copies of nsp8 and held tightly together by eight copies of nsp7. With an internal diameter of approximately 30 angstroms, the central channel has dimensions and positive electrostatic properties favorable for nucleic acid binding, implying that its role is to confer processivity on RNA-dependent RNA polymerase.
The line below this paragraph, {{ABSTRACT_PUBMED_16228002}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16228002 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16228002}}


==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Sars-cov]]
[[Category: Sars-cov]]
[[Category: Super-complex]]
[[Category: Super-complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:03:28 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:00:06 2008''