2aoz: Difference between revisions

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[[Image:2aoz.gif|left|200px]]
{{Seed}}
[[Image:2aoz.png|left|200px]]


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{{STRUCTURE_2aoz|  PDB=2aoz  |  SCENE=  }}  
{{STRUCTURE_2aoz|  PDB=2aoz  |  SCENE=  }}  


'''Crystal structure of the myotoxin-II from Atropoides nummifer venom'''
===Crystal structure of the myotoxin-II from Atropoides nummifer venom===




==Overview==
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Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural basis for their toxic activity is still only partially understood, the structure of myotoxin II, a monomeric Lys49 PLA2 homologue from Atropoides nummifer, has been determined at 2.08 angstroms resolution and the anion-binding site has been characterized.
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{{ABSTRACT_PUBMED_16682766}}


==About this Structure==
==About this Structure==
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[[Category: Phospholipase a2]]
[[Category: Phospholipase a2]]
[[Category: X-ray diffration]]
[[Category: X-ray diffration]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:18:14 2008''
 
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