2azr: Difference between revisions

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-[[Image:2azr.gif|left|200px]]
+{{Seed}}
+[[Image:2azr.png|left|200px]]
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 {{STRUCTURE_2azr|  PDB=2azr  |  SCENE=  }}
-'''Crystal structure of PTP1B with Bicyclic Thiophene inhibitor'''
+===Crystal structure of PTP1B with Bicyclic Thiophene inhibitor===
-==Overview==
+<!--
-A novel pyridothiophene inhibitor of PTP1B was discovered by rational screening of phosphotyrosine mimics at high micromolar concentrations. The potency of this lead compound has been improved significantly by medicinal chemistry guided by X-ray crystallography and molecular modeling. Excellent consistency has been observed between structure-activity relationships and structural information from PTP1B-inhibitor complexes.
+The line below this paragraph, {{ABSTRACT_PUBMED_16303309}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16303309 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16303309}}
 ==About this Structure==
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 [[Category: Hydrolyase]]
 [[Category: Protein tyrosine phosphatase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:40:19 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:25:25 2008''

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