2b7m: Difference between revisions

Line 1:

[[Image:2b7m.~~gif~~|left|200px]]

[[Image:2b7m.png|left|200px]]

<!--

Line 9:

Line 10:

~~'''~~Crystal Structure of the S. cerevisiae Exocyst Component Exo70p~~'''~~

===Crystal Structure of the S. cerevisiae Exocyst Component Exo70p===

~~==Overview==~~

<!--

The ~~exocyst is an evolutionarily conserved multiprotein complex required for the targeting and docking of post-Golgi vesicles to the plasma membrane. Through its interactions with a variety of proteins~~, ~~including small GTPases~~, the ~~exocyst is thought~~ to ~~integrate signals from~~ the ~~cell and signal that vesicles arriving~~ at ~~the plasma membrane are ready for fusion~~. Here we describe the three-dimensional crystal structure of one of the components of the exocyst, Exo70p, from Saccharomyces cerevisiae at 3.5A resolution. Exo70p binds the small GTPase Rho3p in a GTP-dependent manner with an equilibrium dissociation constant of approximately 70 microM. ~~Exo70p is an extended rod approximately 155 angstroms in length composed principally of alpha helices~~, ~~and~~ is ~~a novel fold. The structure provides a first view of the Exo70 protein family and provides a framework to study~~ the ~~molecular function of this exocyst component~~.

The line below this paragraph, {{ABSTRACT_PUBMED_16359701}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 16359701 is the PubMed ID number.

-->

==About this Structure==

Line 28:

Line 32:

[[Category: Exocyst]]

[[Category: Exocytosis]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 19~~:57:25 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:37:14 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:2b7m.gif|left|200px]]
+{{Seed}}
+[[Image:2b7m.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2b7m|  PDB=2b7m  |  SCENE=  }}
-'''Crystal Structure of the S. cerevisiae Exocyst Component Exo70p'''
+===Crystal Structure of the S. cerevisiae Exocyst Component Exo70p===
-==Overview==
+<!--
-The exocyst is an evolutionarily conserved multiprotein complex required for the targeting and docking of post-Golgi vesicles to the plasma membrane. Through its interactions with a variety of proteins, including small GTPases, the exocyst is thought to integrate signals from the cell and signal that vesicles arriving at the plasma membrane are ready for fusion. Here we describe the three-dimensional crystal structure of one of the components of the exocyst, Exo70p, from Saccharomyces cerevisiae at 3.5A resolution. Exo70p binds the small GTPase Rho3p in a GTP-dependent manner with an equilibrium dissociation constant of approximately 70 microM. Exo70p is an extended rod approximately 155 angstroms in length composed principally of alpha helices, and is a novel fold. The structure provides a first view of the Exo70 protein family and provides a framework to study the molecular function of this exocyst component.
+The line below this paragraph, {{ABSTRACT_PUBMED_16359701}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16359701 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16359701}}
 ==About this Structure==
@@ Line 28: / Line 32: @@
 [[Category: Exocyst]]
 [[Category: Exocytosis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:57:25 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:37:14 2008''