2bkt: Difference between revisions

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[[Image:2bkt.gif|left|200px]]
{{Seed}}
[[Image:2bkt.png|left|200px]]


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{{STRUCTURE_2bkt|  PDB=2bkt  |  SCENE=  }}  
{{STRUCTURE_2bkt|  PDB=2bkt  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF RENIN-PF00257567 COMPLEX'''
===CRYSTAL STRUCTURE OF RENIN-PF00257567 COMPLEX===




==Overview==
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We have found that both enantiomeric configurations of the 6-alkoxymethyl-1-aryl-2-piperazinone scaffold display equipotent renin inhibition activity and similar SAR patterns. This enantiomeric flexibility is in contrast to a previously reported 3-alkoxymethyl-4-arylpiperidine scaffold.
The line below this paragraph, {{ABSTRACT_PUBMED_15837327}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_15837327}}


==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Renin]]
[[Category: Renin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:25:37 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:06:41 2008''