2bop: Difference between revisions

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[[Image:2bop.gif|left|200px]]
{{Seed}}
[[Image:2bop.png|left|200px]]


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{{STRUCTURE_2bop|  PDB=2bop  |  SCENE=  }}  
{{STRUCTURE_2bop|  PDB=2bop  |  SCENE=  }}  


'''CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET'''
===CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET===




==Overview==
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The dominant transcriptional regulator of the papillomaviruses, E2, binds to its specific DNA target through a previously unobserved dimeric antiparallel beta-barrel. The DNA is severely but smoothly bent over the barrel by the interaction of successive major grooves with a pair of symmetrically disposed alpha-helices. The specific interface is an 'interwoven' network of interactions where the identifying base pairs of the target contact more than one amino-acid side chain and the discriminating amino acids interact with more than one base pair.
The line below this paragraph, {{ABSTRACT_PUBMED_1328886}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 1328886 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1328886}}


==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:35:05 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:57:05 2008''
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