2c68: Difference between revisions

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-[[Image:2c68.gif|left|200px]]
+{{Seed}}
+[[Image:2c68.png|left|200px]]
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 {{STRUCTURE_2c68|  PDB=2c68  |  SCENE=  }}
-'''CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR'''
+===CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR===
-==Overview==
+<!--
-Crystallographic and modelling data, in conjunction with a medicinal chemistry template-hopping approach, led to the identification of a series of novel and potent inhibitors of human cyclin-dependent kinase 2 (CDK2), with selectivity over glycogen synthase kinase-3beta (GSK-3beta). One example had a CDK2 IC(50) of 120 nM and showed selectivity over GSK-3beta of 167-fold.
+The line below this paragraph, {{ABSTRACT_PUBMED_16325401}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16325401 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16325401}}
 ==About this Structure==
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 [[Category: Transferase]]
 [[Category: Triazolopyrimidine inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 21:19:13 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:00:33 2008''

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