2dc3: Difference between revisions

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[[Image:2dc3.gif|left|200px]]
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[[Image:2dc3.png|left|200px]]


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{{STRUCTURE_2dc3|  PDB=2dc3  |  SCENE=  }}  
{{STRUCTURE_2dc3|  PDB=2dc3  |  SCENE=  }}  


'''Crystal structure of human cytoglobin at 1.68 angstroms resolution'''
===Crystal structure of human cytoglobin at 1.68 angstroms resolution===




==Overview==
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Cytoglobin (Cgb) is a recently discovered member of the vertebrate haem-containing globin family. The structure of a new crystal form of wild-type human Cgb (space group C2) was determined at a resolution of 1.68 Angstrom. The results show the presence of an additional helix in the N-terminal residues (4-20) prior to the A helix and an ordered loop structure in the C-terminal region (168-188), while these extended peptides were invisible owing to disorder in the previously reported structures using a P3(2)21 crystal at a resolution of 2.4 Angstrom. A detailed comparison of the two crystal structures shows differences in the conformation of the residues (i.e. Arg84) in the haem environment owing to a different dimeric arrangement.
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{{ABSTRACT_PUBMED_16699195}}


==About this Structure==
==About this Structure==
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[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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Revision as of 19:05, 28 July 2008

File:2dc3.png

Template:STRUCTURE 2dc3

Crystal structure of human cytoglobin at 1.68 angstroms resolution

Template:ABSTRACT PUBMED 16699195

About this Structure

2DC3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:16699195

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