2dde: Difference between revisions

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[[Image:2dde.gif|left|200px]]
{{Seed}}
[[Image:2dde.png|left|200px]]


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{{STRUCTURE_2dde|  PDB=2dde  |  SCENE=  }}  
{{STRUCTURE_2dde|  PDB=2dde  |  SCENE=  }}  


'''Structure of cinnamycin complexed with lysophosphatidylethanolamine'''
===Structure of cinnamycin complexed with lysophosphatidylethanolamine===




==Overview==
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The three-dimensional structure of a complex of cinnamycin, a 19-amino acid residue immunopotentiator peptide, and lysophosphatidylethanolamine was determined by 1H-NMR. The complex was cylindrical in shape, 11 A in diameter and 26 A in length, excluding the acyl chain of the phospholipid. The peptide had a hydrophobic pocket surrounded by residues Phe-7 through Ala(S)-14 to bind to the head group of the ligand. Fitting of the head group to the hydrophobic pocket was so good that other than a glycerophosphoethanolamine head group would be unable to fit the pocket. The goodness of the fitting is compatible with the strict specificity of ligand binding of the peptide.
The line below this paragraph, {{ABSTRACT_PUBMED_8882709}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8882709 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8882709}}


==About this Structure==
==About this Structure==
2DDE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA].  
2DDE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA].  


==Reference==
==Reference==
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[[Category: Lipid binding]]
[[Category: Lipid binding]]
[[Category: Phosphatidylethanolamine]]
[[Category: Phosphatidylethanolamine]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 00:13:03 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:49:40 2008''
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