2dxs: Difference between revisions

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-[[Image:2dxs.jpg|left|200px]]
+{{Seed}}
+[[Image:2dxs.png|left|200px]]
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 {{STRUCTURE_2dxs|  PDB=2dxs  |  SCENE=  }}
-'''Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor'''
+===Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor===
-==Overview==
+<!--
-We report a new series of hepatitis C virus NS5B RNA polymerase inhibitors containing a conformationally constrained tetracyclic scaffold. SAR studies led to the identification of 6,7-dihydro-5H-benzo[5,6][1,4]diazepino[7,1-a]indoles (19 and 20) bearing a basic pendent group with high biochemical and cellular potencies. These compounds displayed a very small shift in cellular potency when the replicon assay was performed in the presence of human serum albumin.
+The line below this paragraph, {{ABSTRACT_PUBMED_17125247}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17125247 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17125247}}
 ==About this Structure==
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 [[Category: Ns5b]]
 [[Category: Rna polymerase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 01:35:01 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:42:30 2008''

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