2g0d: Difference between revisions

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[[Image:2g0d.gif|left|200px]]
{{Seed}}
[[Image:2g0d.png|left|200px]]


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{{STRUCTURE_2g0d|  PDB=2g0d  |  SCENE=  }}  
{{STRUCTURE_2g0d|  PDB=2g0d  |  SCENE=  }}  


'''Nisin cyclase'''
===Nisin cyclase===




==Overview==
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Nisin is a posttranslationally modified antimicrobial peptide that is widely used as a food preservative. It contains five cyclic thioethers of varying sizes that are installed by a single enzyme, NisC. Reported here are the in vitro reconstitution of the cyclization process and the x-ray crystal structure of the NisC enzyme. The structure reveals similarities in fold and substrate activation with mammalian farnesyl transferases, suggesting that human homologs of NisC posttranslationally modify a cysteine of a protein substrate.
The line below this paragraph, {{ABSTRACT_PUBMED_16527981}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16527981 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16527981}}


==About this Structure==
==About this Structure==
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[[Category: Alpha barrel]]
[[Category: Alpha barrel]]
[[Category: Alpha toroid]]
[[Category: Alpha toroid]]
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