2gcu: Difference between revisions

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[[Image:2gcu.gif|left|200px]]
{{Seed}}
[[Image:2gcu.png|left|200px]]


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{{STRUCTURE_2gcu|  PDB=2gcu  |  SCENE=  }}  
{{STRUCTURE_2gcu|  PDB=2gcu  |  SCENE=  }}  


'''X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580'''
===X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580===




==Overview==
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The protein product of gene At1g53580 from Arabidopsis thaliana possesses 54% sequence identity to a human enzyme that has been implicated in the rare disorder ethylmalonic encephalopathy. The structure of the At1g53580 protein has been solved to a nominal resolution of 1.48 Angstrom. This structure reveals tertiary structure differences between the ETHE1-like enzyme and glyoxalase II enzymes that are likely to account for differences in reaction chemistry and multimeric state between the two types of enzymes. In addition, the Arabidopsis ETHE1 protein is used as a model to explain the significance of several mutations in the human enzyme that have been observed in patients with ethylmalonic encephalopathy.
The line below this paragraph, {{ABSTRACT_PUBMED_16929096}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16929096 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16929096}}


==About this Structure==
==About this Structure==
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[[Category: Psi]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 04:57:35 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:36:17 2008''
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