2gf1: Difference between revisions

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[[Image:2gf1.jpg|left|200px]]
{{Seed}}
[[Image:2gf1.png|left|200px]]


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{{STRUCTURE_2gf1|  PDB=2gf1  |  SCENE=  }}  
{{STRUCTURE_2gf1|  PDB=2gf1  |  SCENE=  }}  


'''SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY'''
===SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY===




==Overview==
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The solution structure of human insulin-like growth factor 1 has been investigated with a combination of nuclear magnetic resonance and restrained molecular dynamics methods. The results show that the solution structure is similar to that of insulin, but minor differences exist. The regions homologous to insulin are well-defined, while the remainder of the molecule exhibits greater disorder. The resultant structures have been used to visualize the sites for interaction with a number of physiologically important proteins.
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{{ABSTRACT_PUBMED_2036417}}


==About this Structure==
==About this Structure==
2GF1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF1 OCA].  
2GF1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF1 OCA].  


==Reference==
==Reference==
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[[Category: Harvey, T S.]]
[[Category: Harvey, T S.]]
[[Category: Growth factor]]
[[Category: Growth factor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 05:01:47 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:06:00 2008''