2gic: Difference between revisions

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[[Image:2gic.gif|left|200px]]
{{Seed}}
[[Image:2gic.png|left|200px]]


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{{STRUCTURE_2gic|  PDB=2gic  |  SCENE=  }}  
{{STRUCTURE_2gic|  PDB=2gic  |  SCENE=  }}  


'''Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex'''
===Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex===




==Overview==
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Vesicular stomatitis virus is a negative-stranded RNA virus. Its nucleoprotein (N) binds the viral genomic RNA and is involved in multiple functions including transcription, replication, and assembly. We have determined a 2.9 angstrom structure of a complex containing 10 molecules of the N protein and 90 bases of RNA. The RNA is tightly sequestered in a cavity at the interface between two lobes of the N protein. This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary.
The line below this paragraph, {{ABSTRACT_PUBMED_16778022}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16778022 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16778022}}


==About this Structure==
==About this Structure==
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[[Category: Nucleocapsid]]
[[Category: Nucleocapsid]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 05:08:24 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:01:50 2008''
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