2obv: Difference between revisions

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[[Image:2obv.gif|left|200px]]<br />

[[Image:2obv.gif|left|200px]]<br /><applet load="2obv" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="2obv" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="2obv, resolution 2.05Å" />

'''Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product'''<br />

~~==Disease==~~

Known diseases associated with this structure: Hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase I/III deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]], Methionine adenosyltransferase deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]]

==About this Structure==

2OBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NA, SAM and PG4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].

2OBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=SAM:'>SAM</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].

[[Category: Homo sapiens]]

[[Category: Methionine adenosyltransferase]]

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[[Category: synthetase]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Mon Nov 12~~ 23:08~~:52 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:38:08 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2obv.gif|left|200px]]<br />
+[[Image:2obv.gif|left|200px]]<br /><applet load="2obv" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="2obv" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="2obv, resolution 2.05&Aring;" />
 '''Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product'''<br />
-==Disease==
-Known diseases associated with this structure: Hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase I/III deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]], Methionine adenosyltransferase deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]]
 ==About this Structure==
-OBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NA, SAM and PG4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].
+OBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=SAM:'>SAM</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].
 [[Category: Homo sapiens]]
 [[Category: Methionine adenosyltransferase]]
@@ Line 33: / Line 29: @@
 [[Category: synthetase]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:08:52 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 14:38:08 2008''