2gx9: Difference between revisions

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[[Image:2gx9.gif|left|200px]]
{{Seed}}
[[Image:2gx9.png|left|200px]]


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{{STRUCTURE_2gx9|  PDB=2gx9  |  SCENE=  }}  
{{STRUCTURE_2gx9|  PDB=2gx9  |  SCENE=  }}  


'''X-ray strucutre of influenza virus NS1 effector domain'''
===X-ray strucutre of influenza virus NS1 effector domain===




==Overview==
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The nonstructural protein NS1 of influenza virus is an antagonist of host immune responses and is implicated in virulence. It has two domains, an N-terminal double-stranded RNA-binding domain (RBD) and an effector domain crucial for RBD function, for nuclear export and for sequestering messenger RNA-processing proteins. Here we present the crystallographic structure of the effector domain, which has a novel fold and suggests mechanisms for increased virulence in H5N1 strains.
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{{ABSTRACT_PUBMED_16715094}}


==About this Structure==
==About this Structure==
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[[Category: Influenza]]
[[Category: Influenza]]
[[Category: Ns1]]
[[Category: Ns1]]
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