2pho: Difference between revisions
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New page: left|200px<br /> <applet load="2pho" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pho, resolution 1.95Å" /> '''Crystal structure o... |
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[[Image:2pho. | [[Image:2pho.jpg|left|200px]]<br /><applet load="2pho" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2pho" size=" | |||
caption="2pho, resolution 1.95Å" /> | caption="2pho, resolution 1.95Å" /> | ||
'''Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution'''<br /> | '''Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
2PHO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MN and TSZ as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] Full crystallographic information is available from [http:// | 2PHO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=TSZ:'>TSZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHO OCA]. | ||
==Reference== | |||
Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster., Di Costanzo L, Pique ME, Christianson DW, J Am Chem Soc. 2007 May 23;129(20):6388-9. Epub 2007 May 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17469833 17469833] | |||
[[Category: Arginase]] | [[Category: Arginase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: TSZ]] | [[Category: TSZ]] | ||
[[Category: fragment]] | [[Category: fragment]] | ||
[[Category: hydrolase]] | |||
[[Category: inhibitor design]] | [[Category: inhibitor design]] | ||
[[Category: thiosemicarbazide]] | [[Category: thiosemicarbazide]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:23:25 2008'' | ||
