2hqv: Difference between revisions

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[[Image:2hqv.gif|left|200px]]
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[[Image:2hqv.png|left|200px]]


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{{STRUCTURE_2hqv|  PDB=2hqv  |  SCENE=  }}  
{{STRUCTURE_2hqv|  PDB=2hqv  |  SCENE=  }}  


'''X-ray Crystal Structure of Protein AGR_C_4470 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR92.'''
===X-ray Crystal Structure of Protein AGR_C_4470 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR92.===




==Overview==
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We report here the crystal structure at 2.0 A resolution of the AGR_C_4470p protein from the Gram-negative bacterium Agrobacterium tumefaciens. The protein is a tightly associated dimer, each subunit of which bears strong structural homology with the two domains of the heme utilization protein ChuS from Escherichia coli and HemS from Yersinia enterocolitica. Remarkably, the organization of the AGR_C_4470p dimer is the same as that of the two domains in ChuS and HemS, providing structural evidence that these two proteins evolved by gene duplication. However, the binding site for heme, while conserved in HemS and ChuS, is not conserved in AGR_C_4470p, suggesting that it probably has a different function. This is supported by the presence of two homologs of AGR_C_4470p in E. coli, in addition to the ChuS protein.
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{{ABSTRACT_PUBMED_17322535}}


==About this Structure==
==About this Structure==
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[[Category: Q7cx01_agrt5]]
[[Category: Q7cx01_agrt5]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:36:04 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:24:31 2008''

Revision as of 05:24, 29 July 2008

File:2hqv.png

Template:STRUCTURE 2hqv

X-ray Crystal Structure of Protein AGR_C_4470 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR92.

Template:ABSTRACT PUBMED 17322535

About this Structure

2HQV is a Single protein structure of sequence from Agrobacterium tumefaciens. Full crystallographic information is available from OCA.

Reference

Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens., Vorobiev SM, Neely H, Seetharaman J, Ma LC, Xiao R, Acton TB, Montelione GT, Tong L, Protein Sci. 2007 Mar;16(3):535-8. PMID:17322535

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