2qcf: Difference between revisions

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New page: left|200px<br /> <applet load="2qcf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2qcf, resolution 1.22Å" /> '''Crystal structure o...
 
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[[Image:2qcf.gif|left|200px]]<br />
[[Image:2qcf.jpg|left|200px]]<br /><applet load="2qcf" size="350" color="white" frame="true" align="right" spinBox="true"  
<applet load="2qcf" size="450" color="white" frame="true" align="right" spinBox="true"  
caption="2qcf, resolution 1.22&Aring;" />
caption="2qcf, resolution 1.22&Aring;" />
'''Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP'''<br />
'''Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP'''<br />
==Disease==
Known disease associated with this structure: Oroticaciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=258900 258900]]


==About this Structure==
==About this Structure==
2QCF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with S, 5FU and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2QCF OCA].  
2QCF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=S:'>S</scene>, <scene name='pdbligand=5FU:'>5FU</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCF OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
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[[Category: ump synthase]]
[[Category: ump synthase]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:31:55 2007''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:23:00 2008''

Revision as of 10:23, 23 January 2008

File:2qcf.jpg


2qcf, resolution 1.22Å

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP

About this Structure

2QCF is a Single protein structure of sequence from Homo sapiens with S, 5FU and GOL as ligands. Active as Orotidine-5'-phosphate decarboxylase, with EC number 4.1.1.23 Full crystallographic information is available from OCA.

Page seeded by OCA on Wed Jan 23 12:23:00 2008

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