2i6e: Difference between revisions

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[[Image:2i6e.gif|left|200px]]
{{Seed}}
[[Image:2i6e.png|left|200px]]


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{{STRUCTURE_2i6e|  PDB=2i6e  |  SCENE=  }}  
{{STRUCTURE_2i6e|  PDB=2i6e  |  SCENE=  }}  


'''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178'''
===Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178===




==Overview==
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BACKGROUND: Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families, known as Domains of Unknown Function (DUFs) and Uncharacterized Protein Families (UPFs). RESULTS: Crystal structures of two proteins from Deinococcus radiodurans and Streptomyces coelicolor belonging to Pfam protein family DUF178 (ID: PF02621) have been determined using Selenium-Single-wavelength Anomalous Dispersion (Se-SAD). Based on the structure, we have identified the putative function for this family of protein. CONCLUSION: Unexpectedly, we found that DUF178 Pfam is remarkably similar to Pfam family DUF191 suggesting that the sequence-based classification alone may not be sufficient to classify proteins into Pfam families.
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{{ABSTRACT_PUBMED_17908300}}


==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Unknown function]]
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