2iok: Difference between revisions

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-[[Image:2iok.jpg|left|200px]]
+{{Seed}}
+[[Image:2iok.png|left|200px]]
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 {{STRUCTURE_2iok|  PDB=2iok  |  SCENE=  }}
-'''Human estrogen receptor alpha ligand-binding domain in complex with compound 1D'''
+===Human estrogen receptor alpha ligand-binding domain in complex with compound 1D===
-==Overview==
+<!--
-A novel class of indole ligands for estrogen receptor alpha have been discovered which exhibit potent affinity and high selectivity. Substitution of the bazedoxifene skeleton to the linker present in the HTS lead 1a provided 22b which was found to be 130-fold alpha-selective and acted as an antagonist of estradiol activity in uterine tissue and MCF-7 cancer cells.
+The line below this paragraph, {{ABSTRACT_PUBMED_17289385}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17289385 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17289385}}
 ==About this Structure==
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 [[Category: Nuclear receptor]]
 [[Category: Transcription factor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 07:43:26 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:46:35 2008''

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