2j0a: Difference between revisions

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-[[Image:2j0a.jpg|left|200px]]
+{{Seed}}
+[[Image:2j0a.png|left|200px]]
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 {{STRUCTURE_2j0a|  PDB=2j0a  |  SCENE=  }}
-'''STRUCTURE OF THE CATALYTIC DOMAIN OF MOUSE MANIC FRINGE'''
+===STRUCTURE OF THE CATALYTIC DOMAIN OF MOUSE MANIC FRINGE===
-==Overview==
+<!--
-Fringe proteins are beta1,3-N-acetylglucosaminyltransferases that modify Notch receptors, altering their ligand-binding specificity to regulate Notch signaling in development. We present the crystal structure of mouse Manic Fringe bound to UDP and manganese. The structure reveals amino acid residues involved in recognition of donor substrates and catalysis, and a putative binding pocket for acceptor substrates. Mutations of several invariant residues in this pocket impair Fringe activity in vivo.
+The line below this paragraph, {{ABSTRACT_PUBMED_16964258}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16964258 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16964258}}
 ==About this Structure==
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 [[Category: Transferase]]
 [[Category: Transmembrane]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 08:09:28 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:39:57 2008''

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