2nnj: Difference between revisions

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[[Image:2nnj.gif|left|200px]]
{{Seed}}
[[Image:2nnj.png|left|200px]]


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{{STRUCTURE_2nnj|  PDB=2nnj  |  SCENE=  }}  
{{STRUCTURE_2nnj|  PDB=2nnj  |  SCENE=  }}  


'''CYP2C8dH complexed with felodipine'''
===CYP2C8dH complexed with felodipine===


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{{ABSTRACT_PUBMED_18413310}}
==Disease==
Known disease associated with this structure: Rhabdomyolysis, cerivastatin-induced OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601129 601129]]


==About this Structure==
==About this Structure==
2NNJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNJ OCA].  
2NNJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNJ OCA].  
 
==Reference==
Determinants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACID., Schoch GA, Yano JK, Sansen S, Dansette PM, Stout CD, Johnson EF, J Biol Chem. 2008 Jun 20;283(25):17227-37. Epub 2008 Apr 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18413310 18413310]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Unspecific monooxygenase]]
[[Category: Unspecific monooxygenase]]
[[Category: Johnson, E F.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Schoch, G A.]]
[[Category: Stout, C D.]]
[[Category: Yano, J K.]]
[[Category: Cyp2c8]]
[[Category: Cyp2c8]]
[[Category: Electron transport]]
[[Category: Felodipine]]
[[Category: Felodipine]]
[[Category: Human p450 2c8]]
[[Category: Human p450 2c8]]
[[Category: Inhibitor complex]]
[[Category: Inhibitor complex]]
[[Category: Monooxygenase]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase,electron transport]]
[[Category: Oxidoreductase]]
[[Category: Palmitic acid]]
[[Category: Palmitic acid]]
[[Category: Plendil]]
[[Category: Plendil]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:40:13 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 3 20:07:22 2008''

Revision as of 18:07, 3 December 2008

File:2nnj.png

Template:STRUCTURE 2nnj

CYP2C8dH complexed with felodipine

Template:ABSTRACT PUBMED 18413310

Disease

Known disease associated with this structure: Rhabdomyolysis, cerivastatin-induced OMIM:[601129]

About this Structure

2NNJ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Determinants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACID., Schoch GA, Yano JK, Sansen S, Dansette PM, Stout CD, Johnson EF, J Biol Chem. 2008 Jun 20;283(25):17227-37. Epub 2008 Apr 15. PMID:18413310 [[Category: Pdbx_ordinal=, <PDBx:audit_author.]]

Page seeded by OCA on Wed Dec 3 20:07:22 2008

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