2npl: Difference between revisions

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[[Image:2npl.~~gif~~|left|200px]]

[[Image:2npl.png|left|200px]]

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~~'''~~NMR Structure of CARD d2 Domain~~'''~~

===NMR Structure of CARD d2 Domain===

~~==Overview==~~

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The ~~coxsackievirus and adenovirus receptor~~ (~~CAR) mediates entry of coxsackievirus and adenovirus~~. ~~CAR possesses an extracellular region that is comprised of 2 immunoglobulin domains termed CAR-D1 and CAR-D2~~. ~~In the present work, the solution structure of CAR-D2~~, ~~consisting of residues 142-235 of human CAR, has been determined by NMR spectroscopy. CAR-D2~~ is ~~shown to be a beta-sandwich motif comprised of two beta-sheets, which are stabilized by two disulfide bonds. The first beta-sheet is comprised of beta-strands A, B, and E, and~~ the ~~second beta-sheet is comprised of beta-strands C, F, and G~~. ~~A relatively hydrophobic helix is found between beta~~-~~strands C and E, which replaces beta~~-~~strand D of the classical c-type immunoglobulin fold.~~

The line below this paragraph, {{ABSTRACT_PUBMED_17322536}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 17322536 is the PubMed ID number.

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==About this Structure==

2NPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPL OCA].

2NPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPL OCA].

==Reference==

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[[Category: Jiang, S.]]

[[Category: Coxsakievirus and adenovirus receptor]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 09~~:44:48 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:00:36 2008''

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-[[Image:2npl.gif|left|200px]]
+{{Seed}}
+[[Image:2npl.png|left|200px]]
 <!--
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 {{STRUCTURE_2npl|  PDB=2npl  |  SCENE=  }}
-'''NMR Structure of CARD d2 Domain'''
+===NMR Structure of CARD d2 Domain===
-==Overview==
+<!--
-The coxsackievirus and adenovirus receptor (CAR) mediates entry of coxsackievirus and adenovirus. CAR possesses an extracellular region that is comprised of 2 immunoglobulin domains termed CAR-D1 and CAR-D2. In the present work, the solution structure of CAR-D2, consisting of residues 142-235 of human CAR, has been determined by NMR spectroscopy. CAR-D2 is shown to be a beta-sandwich motif comprised of two beta-sheets, which are stabilized by two disulfide bonds. The first beta-sheet is comprised of beta-strands A, B, and E, and the second beta-sheet is comprised of beta-strands C, F, and G. A relatively hydrophobic helix is found between beta-strands C and E, which replaces beta-strand D of the classical c-type immunoglobulin fold.
+The line below this paragraph, {{ABSTRACT_PUBMED_17322536}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17322536 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17322536}}
 ==About this Structure==
-NPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPL OCA].
+NPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPL OCA].
 ==Reference==
@@ Line 25: / Line 29: @@
 [[Category: Jiang, S.]]
 [[Category: Coxsakievirus and adenovirus receptor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:44:48 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:00:36 2008''