2o71: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2o71.gif|left|200px]]
{{Seed}}
[[Image:2o71.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2o71|  PDB=2o71  |  SCENE=  }}  
{{STRUCTURE_2o71|  PDB=2o71  |  SCENE=  }}  


'''Crystal structure of RAIDD DD'''
===Crystal structure of RAIDD DD===




==Overview==
<!--  
Caspase-2 is implicated in stress-induced apoptosis that acts as an upstream initiator of mitochondrial permeabilization. Recent studies have shown that caspase-2 activation requires a molecular complex known as the PIDDosome comprising the p53-inducible protein PIDD, the adapter protein RAIDD and caspase-2. RAIDD has an N-terminal caspase recruitment domain (CARD) that interacts with the CARD of caspase-2 and a C-terminal death domain (DD) that interacts with the DD in PIDD. As a first step towards elucidating the molecular mechanisms of caspase-2 activation, we report the crystal structure of RAIDD DD at 2.0 A resolution. The high-resolution structure reveals important features of RAIDD DD that may be important for DD folding and dynamics and for assembly of the PIDDosome.
The line below this paragraph, {{ABSTRACT_PUBMED_16434054}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16434054 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16434054}}


==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Death domain]]
[[Category: Death domain]]
[[Category: Raidd]]
[[Category: Raidd]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:24:17 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:12:21 2008''
Retrieved from "https://proteopedia.org/2o71"