2of2: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2of2. | {{Seed}} | ||
[[Image:2of2.png|left|200px]] | |||
<!-- | <!-- | ||
| Line 9: | Line 10: | ||
{{STRUCTURE_2of2| PDB=2of2 | SCENE= }} | {{STRUCTURE_2of2| PDB=2of2 | SCENE= }} | ||
===crystal structure of furanopyrimidine 8 bound to lck=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_17276681}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 17276681 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_17276681}} | |||
==Disease== | ==Disease== | ||
| Line 29: | Line 33: | ||
[[Category: Kinase domain]] | [[Category: Kinase domain]] | ||
[[Category: Lck]] | [[Category: Lck]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:45:36 2008'' | |||
Revision as of 15:45, 27 July 2008
crystal structure of furanopyrimidine 8 bound to lck
Template:ABSTRACT PUBMED 17276681
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
2OF2 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties., Martin MW, Newcomb J, Nunes JJ, Bemis JE, McGowan DC, White RD, Buchanan JL, DiMauro EF, Boucher C, Faust T, Hsieh F, Huang X, Lee JH, Schneider S, Turci SM, Zhu X, Bioorg Med Chem Lett. 2007 Apr 15;17(8):2299-304. Epub 2007 Jan 24. PMID:17276681
Page seeded by OCA on Sun Jul 27 18:45:36 2008
