1ytf: Difference between revisions
New page: left|200px<br /> <applet load="1ytf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ytf, resolution 2.500Å" /> '''YEAST TFIIA/TBP/DN... |
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[[Image:1ytf. | [[Image:1ytf.jpg|left|200px]]<br /><applet load="1ytf" size="350" color="white" frame="true" align="right" spinBox="true" | ||
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caption="1ytf, resolution 2.500Å" /> | caption="1ytf, resolution 2.500Å" /> | ||
'''YEAST TFIIA/TBP/DNA COMPLEX'''<br /> | '''YEAST TFIIA/TBP/DNA COMPLEX'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
1YTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTF with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http:// | 1YTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTF with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTF OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:12:36 2008'' | ||
Revision as of 15:12, 15 February 2008
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YEAST TFIIA/TBP/DNA COMPLEX
Overview
The X-ray crystal structure of the transcription factor IIA (TFIIA) in, complex with the TATA-box-binding protein (TBP) and TATA-element DNA is, presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a, four-helix bundle motif that together have a boot-like appearance. The, beta-barrel extends the TBP beta-sheet and bridges over the DNA major, groove immediately upstream of the TATA box. The four-helix bundle, contributes substantially to the surface of the complex available for, interaction with additional transcription factors.
About this Structure
1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010
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