2ph6: Difference between revisions

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-[[Image:2ph6.jpg|left|200px]]
+{{Seed}}
+[[Image:2ph6.png|left|200px]]
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 {{STRUCTURE_2ph6|  PDB=2ph6  |  SCENE=  }}
-'''Crystal Structure of Human Beta Secretase Complexed with inhibitor'''
+===Crystal Structure of Human Beta Secretase Complexed with inhibitor===
-==Overview==
+<!--
-This Letter describes the design and synthesis of tertiary carbinamine macrocyclic inhibitors of the beta-secretase (BACE-1) enzyme. These macrocyclic inhibitors, some of which incorporate novel P2 substituents, display a 2- to 100-fold increase in potency relative to the previously described acyclic analogs while affording greater stability.
+The line below this paragraph, {{ABSTRACT_PUBMED_17482814}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17482814 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17482814}}
 ==About this Structure==
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 [[Category: Bace]]
 [[Category: Hydrolase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:06:10 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:52:44 2008''

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