2pog: Difference between revisions

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[[Image:2pog.jpg|left|200px]]
{{Seed}}
[[Image:2pog.png|left|200px]]


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{{STRUCTURE_2pog|  PDB=2pog  |  SCENE=  }}  
{{STRUCTURE_2pog|  PDB=2pog  |  SCENE=  }}  


'''Benzopyrans as Selective Estrogen Receptor b Agonists (SERBAs). Part 2: Structure Activity Relationship Studies on the Benzopyran Scaffold.'''
===Benzopyrans as Selective Estrogen Receptor b Agonists (SERBAs). Part 2: Structure Activity Relationship Studies on the Benzopyran Scaffold.===




==Overview==
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Benzopyrans are selective estrogen receptor (ER) beta agonists (SERBAs), which bind the ER subtypes alpha and beta in opposite orientations. Here we describe structure-activity relationship studies that led to the discovery of bezopyran 5b. X-ray crystal structures of 5b and a non-selective analog 5c in ERalpha help explain the observed selectivity of the benzopyran platform.
The line below this paragraph, {{ABSTRACT_PUBMED_17485205}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17485205 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17485205}}


==About this Structure==
==About this Structure==
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[[Category: Lipid binding protein]]
[[Category: Lipid binding protein]]
[[Category: Nuclear receptor]]
[[Category: Nuclear receptor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:32:11 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:35:21 2008''
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