1rmd: Difference between revisions

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[[Image:1rmd.gif|left|200px]]<br />

[[Image:1rmd.gif|left|200px]]<br /><applet load="1rmd" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="1rmd" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="1rmd, resolution 2.10Å" />

'''RAG1 DIMERIZATION DOMAIN'''<br />

==Overview==

The crystal structure of the dimerization domain of the V(D)J, recombination-activating protein, RAG1, was solved using zinc anomalous, scattering. The structure reveals an unusual combination of multi-class, zinc-binding motifs, including a zinc RING finger and a C2H2 zinc finger, that together from a single structural domain. The domain also contains a, unique zinc binuclear cluster in place of a normally mononuclear zinc site, in the RING finger. Together, four zinc ions help organize the entire, domain, including the two helices that form the dimer interface.

The crystal structure of the dimerization domain of the V(D)J recombination-activating protein, RAG1, was solved using zinc anomalous scattering. The structure reveals an unusual combination of multi-class zinc-binding motifs, including a zinc RING finger and a C2H2 zinc finger, that together from a single structural domain. The domain also contains a unique zinc binuclear cluster in place of a normally mononuclear zinc site in the RING finger. Together, four zinc ions help organize the entire domain, including the two helices that form the dimer interface.

==About this Structure==

1RMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1RMD OCA].

1RMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RMD OCA].

==Reference==

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[[Category: Mus musculus]]

[[Category: Single protein]]

[[Category: Bellon, S.F.]]

[[Category: Bellon, S F.]]

[[Category: Coleman, J.E.]]

[[Category: Coleman, J E.]]

[[Category: Rodgers, K.K.]]

[[Category: Rodgers, K K.]]

[[Category: Schatz, D.G.]]

[[Category: Schatz, D G.]]

[[Category: Steitz, T.A.]]

[[Category: Steitz, T A.]]

[[Category: ZN]]

[[Category: antibody]]

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[[Category: zinc finger]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Sun Nov 18 09~~:41:~~29 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:52:25 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1rmd.gif|left|200px]]<br />
+[[Image:1rmd.gif|left|200px]]<br /><applet load="1rmd" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1rmd" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1rmd, resolution 2.10&Aring;" />
 '''RAG1 DIMERIZATION DOMAIN'''<br />
 ==Overview==
-The crystal structure of the dimerization domain of the V(D)J, recombination-activating protein, RAG1, was solved using zinc anomalous, scattering. The structure reveals an unusual combination of multi-class, zinc-binding motifs, including a zinc RING finger and a C2H2 zinc finger, that together from a single structural domain. The domain also contains a, unique zinc binuclear cluster in place of a normally mononuclear zinc site, in the RING finger. Together, four zinc ions help organize the entire, domain, including the two helices that form the dimer interface.
+The crystal structure of the dimerization domain of the V(D)J recombination-activating protein, RAG1, was solved using zinc anomalous scattering. The structure reveals an unusual combination of multi-class zinc-binding motifs, including a zinc RING finger and a C2H2 zinc finger, that together from a single structural domain. The domain also contains a unique zinc binuclear cluster in place of a normally mononuclear zinc site in the RING finger. Together, four zinc ions help organize the entire domain, including the two helices that form the dimer interface.
 ==About this Structure==
-RMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RMD OCA].
+RMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RMD OCA].
 ==Reference==
@@ Line 14: / Line 13: @@
 [[Category: Mus musculus]]
 [[Category: Single protein]]
-[[Category: Bellon, S.F.]]
+[[Category: Bellon, S F.]]
-[[Category: Coleman, J.E.]]
+[[Category: Coleman, J E.]]
-[[Category: Rodgers, K.K.]]
+[[Category: Rodgers, K K.]]
-[[Category: Schatz, D.G.]]
+[[Category: Schatz, D G.]]
-[[Category: Steitz, T.A.]]
+[[Category: Steitz, T A.]]
 [[Category: ZN]]
 [[Category: antibody]]
@@ Line 29: / Line 28: @@
 [[Category: zinc finger]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 18 09:41:29 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:52:25 2008''