2r6n: Difference between revisions

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[[Image:2r6n.jpg|left|200px]]
{{Seed}}
[[Image:2r6n.png|left|200px]]


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{{STRUCTURE_2r6n|  PDB=2r6n  |  SCENE=  }}  
{{STRUCTURE_2r6n|  PDB=2r6n  |  SCENE=  }}  


'''Crystal structure of a pyrrolopyrimidine inhibitor in complex with human Cathepsin K'''
===Crystal structure of a pyrrolopyrimidine inhibitor in complex with human Cathepsin K===




==Overview==
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Pyrrolopyrimidine, a novel scaffold, allows to adjust interactions within the S3 subsite of cathepsin K. The core intermediate 10 facilitated the P3 optimization and identified highly potent and selective cathepsin K inhibitors 11-20.
The line below this paragraph, {{ABSTRACT_PUBMED_17911019}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_17911019}}


==About this Structure==
==About this Structure==
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[[Category: Thiol protease]]
[[Category: Thiol protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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