2rjs: Difference between revisions

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-[[Image:2rjs.jpg|left|200px]]
+{{Seed}}
+[[Image:2rjs.png|left|200px]]
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 {{STRUCTURE_2rjs|  PDB=2rjs  |  SCENE=  }}
-'''SgTAM bound to substrate mimic'''
+===SgTAM bound to substrate mimic===
-==Overview==
+<!--
-The synthesis and evaluation of two classes of inhibitors for SgTAM, a 4-methylideneimidazole-5-one (MIO) containing tyrosine aminomutase, are described. A mechanism-based strategy was used to design analogs that mimic the substrate or product of the reaction and form covalent interactions with the enzyme through the MIO prosthetic group. The analogs were characterized by measuring inhibition constants and X-ray crystallographic structural analysis of the co-complexes bound to the aminomutase, SgTAM.
+The line below this paragraph, {{ABSTRACT_PUBMED_18078753}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18078753 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18078753}}
 ==About this Structure==
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 [[Category: Isomerase]]
 [[Category: Mio]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 17:03:11 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:05:30 2008''

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