1a79: Difference between revisions

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[[Image:1a79.jpg|left|200px]]<br /><applet load="1a79" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1a79.jpg|left|200px]]<br /><applet load="1a79" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1a79, resolution 2.28Å" />

'''CRYSTAL STRUCTURE OF THE TRNA SPLICING ENDONUCLEASE FROM METHANOCOCCUS JANNASCHII'''<br />

==Overview==

The splicing of transfer RNA precursors is similar in Eucarya and Archaea., In both kingdoms an endonuclease recognizes the splice sites and releases, the intron, but the mechanism of splice site recognition is different in, each kingdom. The crystal structure of the endonuclease from the archaeon, Methanococcus jannaschii was determined to a resolution of 2.3 angstroms., The structure indicates that the cleavage reaction is similar to that of, ribonuclease A and the arrangement of the active sites is conserved, between the archaeal and eucaryal enzymes. These results suggest an, evolutionary pathway for splice site recognition.

The splicing of transfer RNA precursors is similar in Eucarya and Archaea. In both kingdoms an endonuclease recognizes the splice sites and releases the intron, but the mechanism of splice site recognition is different in each kingdom. The crystal structure of the endonuclease from the archaeon Methanococcus jannaschii was determined to a resolution of 2.3 angstroms. The structure indicates that the cleavage reaction is similar to that of ribonuclease A and the arrangement of the active sites is conserved between the archaeal and eucaryal enzymes. These results suggest an evolutionary pathway for splice site recognition.

==About this Structure==

1A79 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with SO4 and AU as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1A79 OCA].

1A79 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=AU:'>AU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A79 OCA].

==Reference==

Line 13:

[[Category: Methanocaldococcus jannaschii]]

[[Category: Single protein]]

[[Category: Abelson, J.N.]]

[[Category: Abelson, J N.]]

[[Category: Li, H.]]

[[Category: Trotta, C.R.]]

[[Category: Trotta, C R.]]

[[Category: AU]]

[[Category: SO4]]

Line 21:

[[Category: trna endonuclease]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 10~~:39:~~37 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:41 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1a79.jpg|left|200px]]<br /><applet load="1a79" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1a79.jpg|left|200px]]<br /><applet load="1a79" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1a79, resolution 2.28&Aring;" />
 '''CRYSTAL STRUCTURE OF THE TRNA SPLICING ENDONUCLEASE FROM METHANOCOCCUS JANNASCHII'''<br />
 ==Overview==
-The splicing of transfer RNA precursors is similar in Eucarya and Archaea., In both kingdoms an endonuclease recognizes the splice sites and releases, the intron, but the mechanism of splice site recognition is different in, each kingdom. The crystal structure of the endonuclease from the archaeon, Methanococcus jannaschii was determined to a resolution of 2.3 angstroms., The structure indicates that the cleavage reaction is similar to that of, ribonuclease A and the arrangement of the active sites is conserved, between the archaeal and eucaryal enzymes. These results suggest an, evolutionary pathway for splice site recognition.
+The splicing of transfer RNA precursors is similar in Eucarya and Archaea. In both kingdoms an endonuclease recognizes the splice sites and releases the intron, but the mechanism of splice site recognition is different in each kingdom. The crystal structure of the endonuclease from the archaeon Methanococcus jannaschii was determined to a resolution of 2.3 angstroms. The structure indicates that the cleavage reaction is similar to that of ribonuclease A and the arrangement of the active sites is conserved between the archaeal and eucaryal enzymes. These results suggest an evolutionary pathway for splice site recognition.
 ==About this Structure==
-A79 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with SO4 and AU as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A79 OCA].
+A79 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=AU:'>AU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A79 OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Methanocaldococcus jannaschii]]
 [[Category: Single protein]]
-[[Category: Abelson, J.N.]]
+[[Category: Abelson, J N.]]
 [[Category: Li, H.]]
-[[Category: Trotta, C.R.]]
+[[Category: Trotta, C R.]]
 [[Category: AU]]
 [[Category: SO4]]
@@ Line 21: / Line 21: @@
 [[Category: trna endonuclease]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 10:39:37 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:41 2008''