351d: Difference between revisions

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[[Image:351d.gif|left|200px]]
{{Seed}}
[[Image:351d.png|left|200px]]


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{{STRUCTURE_351d|  PDB=351d  |  SCENE=  }}  
{{STRUCTURE_351d|  PDB=351d  |  SCENE=  }}  


'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''
===X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE===




==Overview==
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Hexammine ions are strong inducers of the transition from the B-form to the left-handed Z-form in DNA. Here the structure of d(CACGCG). d(CGCGTG) obtained from crystals grown from a drop containing [Ru(NH3)6]Cl3 is reported. The structure is clearly characterized as Z-DNA. When compared with the structure of d(CACGCG).d(CGCGTG)/MgCl2 and that of d(CGCGCG)2, subtle differences are seen, most noticeably in the water structure. Since stable well diffracting crystals grow easily in the presence of [Ru(NH3)6]Cl3 and since this ion is not visible in the electron density it is concluded that the ion plays a non-specific role in stabilizing Z-DNA.
The line below this paragraph, {{ABSTRACT_PUBMED_9761846}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9761846 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9761846}}


==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Z-dna]]
[[Category: Z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:26:21 2008''
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