353d: Difference between revisions

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[[Image:353d.gif|left|200px]]
{{Seed}}
[[Image:353d.png|left|200px]]


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{{STRUCTURE_353d|  PDB=353d  |  SCENE=  }}  
{{STRUCTURE_353d|  PDB=353d  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE'''
===CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE===




==Overview==
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This is the first high resolution crystal structure of an RNA molecule made by solid phase chemical synthesis and representing a natural RNA. The structure of the domain A of Thermus flavus ribosomal 5S RNA is refined to R = 18% at 2.4 A including 159 solvent molecules. Most of the 2'-hydroxyl groups as well as the phosphate oxygens are involved either in specific hydrogen bonds in intermolecular contacts or to solvent molecules. The two U-G and G-U base-pairs are stabilized by H-bonds supplied via three water molecules to compensate for the lack of base-pair hydrogen bonds. The structure shows for the first time in detail the importance of highly ordered internal water in stabilizing an RNA structure.
The line below this paragraph, {{ABSTRACT_PUBMED_8082756}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8082756 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8082756}}


==About this Structure==
==About this Structure==
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[[Category: A-rna]]
[[Category: A-rna]]
[[Category: Double strand]]
[[Category: Double strand]]
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