3bue: Difference between revisions

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[[Image:3bue.jpg|left|200px]]
{{Seed}}
[[Image:3bue.png|left|200px]]


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{{STRUCTURE_3bue|  PDB=3bue  |  SCENE=  }}  
{{STRUCTURE_3bue|  PDB=3bue  |  SCENE=  }}  


'''Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis'''
===Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis===




==Overview==
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The gene product of an open reading frame Rv1657 from Mycobacterium tuberculosis is a putative arginine repressor protein (ArgR), a transcriptional factor that regulates the expression of arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a C-terminal domain was crystallized using the hanging-drop vapour-diffusion method. Diffraction data were collected and processed to a resolution of 2.15 A. The crystals belong to space group P1 and the Matthews coefficient suggests that the crystals contain six C-terminal domain molecules per unit cell. Previous structural and biochemical studies on the arginine repressor proteins from other organisms have likewise shown the presence of six molecules per unit cell.
The line below this paragraph, {{ABSTRACT_PUBMED_18703843}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_18703843}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis., Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN, Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):950-6. Epub 2008, Aug 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18703843 18703843]
Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18007044 18007044]
Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18007044 18007044]
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 21:06:53 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 3 10:33:48 2008''

Revision as of 07:33, 3 September 2008

File:3bue.png

Template:STRUCTURE 3bue

Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis

Template:ABSTRACT PUBMED 18703843

About this Structure

3BUE is a Single protein structure of sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

Reference

Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis., Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN, Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):950-6. Epub 2008, Aug 13. PMID:18703843

Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:18007044

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