3byz: Difference between revisions

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[[Image:3byz.~~jpg~~|left|200px]]

[[Image:3byz.png|left|200px]]

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~~'''~~2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors~~'''~~

===2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors===

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The line below this paragraph, {{ABSTRACT_PUBMED_18419108}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 18419108 is the PubMed ID number.

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==About this Structure==

3BYZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYZ OCA].

==Reference==

2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice., Johansson L, Fotsch C, Bartberger MD, Castro VM, Chen M, Emery M, Gustafsson S, Hale C, Hickman D, Homan E, Jordan SR, Komorowski R, Li A, McRae K, Moniz G, Matsumoto G, Orihuela C, Palm G, Veniant M, Wang M, Williams M, Zhang J, J Med Chem. 2008 May 22;51(10):2933-43. Epub 2008 Apr 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18419108 18419108]

[[Category: 11-beta-hydroxysteroid dehydrogenase]]

[[Category: Homo sapiens]]

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[[Category: Steroid metabolism]]

[[Category: Transmembrane]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May~~ ~~4 21~~:13:02 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:04:10 2008''

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-[[Image:3byz.jpg|left|200px]]
+{{Seed}}
+[[Image:3byz.png|left|200px]]
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 {{STRUCTURE_3byz|  PDB=3byz  |  SCENE=  }}
-'''2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors'''
+===2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors===
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18419108}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18419108 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18419108}}
 ==About this Structure==
 BYZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYZ OCA].
+==Reference==
+-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice., Johansson L, Fotsch C, Bartberger MD, Castro VM, Chen M, Emery M, Gustafsson S, Hale C, Hickman D, Homan E, Jordan SR, Komorowski R, Li A, McRae K, Moniz G, Matsumoto G, Orihuela C, Palm G, Veniant M, Wang M, Williams M, Zhang J, J Med Chem. 2008 May 22;51(10):2933-43. Epub 2008 Apr 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18419108 18419108]
 [[Category: 11-beta-hydroxysteroid dehydrogenase]]
 [[Category: Homo sapiens]]
@@ Line 33: / Line 43: @@
 [[Category: Steroid metabolism]]
 [[Category: Transmembrane]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 21:13:02 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 22:04:10 2008''