3cbh: Difference between revisions

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{{STRUCTURE_3cbh|  PDB=3cbh  |  SCENE=  }}  
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'''THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI'''
===THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI===




==Overview==
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The enzymatic degradation of cellulose is an important process, both ecologically and commercially. The three-dimensional structure of a cellulase, the enzymatic core of CBHII from the fungus Trichoderma reesei reveals an alpha-beta protein with a fold similar to but different from the widely occurring barrel topology first observed in triose phosphate isomerase. The active site of CBHII is located at the carboxyl-terminal end of a parallel beta barrel, in an enclosed tunnel through which the cellulose threads. Two aspartic acid residues, located in the center of the tunnel are the probable catalytic residues.
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{{ABSTRACT_PUBMED_2377893}}


==About this Structure==
==About this Structure==
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[[Category: Jones, T A.]]
[[Category: Jones, T A.]]
[[Category: Rouvinen, J.]]
[[Category: Rouvinen, J.]]
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Revision as of 17:55, 27 July 2008

File:3cbh.png

Template:STRUCTURE 3cbh

THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI

Template:ABSTRACT PUBMED 2377893

About this Structure

3CBH is a Single protein structure of sequence from Hypocrea jecorina. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of cellobiohydrolase II from Trichoderma reesei., Rouvinen J, Bergfors T, Teeri T, Knowles JK, Jones TA, Science. 1990 Jul 27;249(4967):380-6. PMID:2377893

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