7rsa: Difference between revisions

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[[Image:7rsa.gif|left|200px]]
{{Seed}}
[[Image:7rsa.png|left|200px]]


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{{STRUCTURE_7rsa|  PDB=7rsa  |  SCENE=  }}  
{{STRUCTURE_7rsa|  PDB=7rsa  |  SCENE=  }}  


'''STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS'''
===STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS===




==Overview==
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The structure of phosphate-free bovine ribonuclease A has been refined at 1.26-A resolution by a restrained least-squares procedure to a final R factor of 0.15. X-ray diffraction data were collected with an electronic position-sensitive detector. The final model consists of all atoms in the polypeptide chain including hydrogens, 188 water sites with full or partial occupancy, and a single molecule of 2-methyl-2-propanol. Thirteen side chains were modeled with two alternate conformations. Major changes to the active site include the addition of two waters in the phosphate-binding pocket, disordering of Gln-11, and tilting of the imidazole ring of His-119. The structure of the protein and of the associated solvent was extensively compared with three other high-resolution, refined structures of this enzyme.
The line below this paragraph, {{ABSTRACT_PUBMED_3401445}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 3401445 is the PubMed ID number.
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{{ABSTRACT_PUBMED_3401445}}


==About this Structure==
==About this Structure==
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[[Category: Gilliland, G L.]]
[[Category: Gilliland, G L.]]
[[Category: Wlodawer, A.]]
[[Category: Wlodawer, A.]]
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