2uvz: Difference between revisions

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-[[Image:2uvz.jpg|left|200px]]
+{{Seed}}
+[[Image:2uvz.png|left|200px]]
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 {{STRUCTURE_2uvz|  PDB=2uvz  |  SCENE=  }}
-'''STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH C-PHENYL-C-(4-(9H-PURIN-6-YL)-PHENYL)-METHYLAMINE'''
+===STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH C-PHENYL-C-(4-(9H-PURIN-6-YL)-PHENYL)-METHYLAMINE===
-==Overview==
+<!--
--phenylpurines were identified as novel, ATP-competitive inhibitors of protein kinase B (PKB/Akt) from a fragment-based screen and were rapidly progressed to potent compounds using iterative protein-ligand crystallography with a PKA-PKB chimeric protein. An elaborated lead compound showed cell growth inhibition and effects on cellular signaling pathways characteristic of PKB inhibition.
+The line below this paragraph, {{ABSTRACT_PUBMED_17451235}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17451235 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17451235}}
 ==About this Structure==
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 [[Category: Transferase]]
 [[Category: Transferase/inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:30:14 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:44:18 2008''

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