Sandbox 46: Difference between revisions

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Revision as of 19:12, 10 October 2008

Template:STRUCTURE 1w68 Template:STRUCTURE 1w69

Mouse Ribonucleotide Reductase

Protein ID:

1w68 (under oxidizing conditions)

1w69 (under reducing conditions)

Introduction

Structual Properties

While both forms of this enzyme both interact with iron, there are some structural differences due to the different conditions.

1w68: 16 α-helices 8 β-turns

1w69: 15 α-helices 10 β-turns

Protein Sequence

For the enzyme under oxidizing conditions (1w68):

VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFA ASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVK KKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFA CLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFR VENPF

For the enzyme under reducing conditions(1w69):

VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFA ASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVK KKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFA CLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFR VENPF

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Sandbox 46: Difference between revisions

Revision as of 19:12, 10 October 2008

Contents

Mouse Ribonucleotide Reductase

Introduction

Structual Properties

Protein Sequence

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@@ Line 1: / Line 1: @@
+{{STRUCTURE_1w68 |  PDB=1w68  |  SCENE=  }}
+{{STRUCTURE_1w69 |  PDB=1w69  |  SCENE=  }}
+==Mouse Ribonucleotide Reductase ==
+Protein ID:
+w68 (under oxidizing conditions)
+w69 (under reducing conditions)
+==Introduction==
+==Structual Properties==
+While both forms of this enzyme both interact with iron, there are some structural differences due to the different conditions.
+w68:
+α-helices
+β-turns
+w69:
+α-helices
+β-turns
+==Protein Sequence==
+For the enzyme under oxidizing conditions (1w68):
+VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFA
+ASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVK
+KKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFA
+CLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFR
+VENPF
+For the enzyme under reducing conditions(1w69):
+VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFA
+ASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVK
+KKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFA
+CLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFR
+VENPF
+==This is a placeholder==
+This is a placeholder text to help you get started in
+placing a Jmol applet on your page. At any time, click
+"Show Preview" at the bottom of this page to see how it goes.
+Replace the PDB id after the STRUCTURE_ and after PDB= to load
+and display another structure.