1bj7: Difference between revisions

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[[Image:1bj7.gif|left|200px]]<br /><applet load="1bj7" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1bj7.gif|left|200px]]<br /><applet load="1bj7" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1bj7, resolution 1.8Å" />

'''BOVINE LIPOCALIN ALLERGEN BOS D 2'''<br />

==Overview==

The three-dimensional structure of the major bovine allergen Bos d 2 has, been determined by using x-ray diffraction at 1.8-A resolution., Structurally Bos d 2 is a member of the lipocalin family comprising, proteins with transport functions. There is a flat small cavity inside the, Bos d 2 protein core suitable for ligand binding, and it is possible that, Glu115 and Asn37 inside the core are able to make hydrogen bonds with the, ligand. Many allergens from different animals belong to the lipocalin, family. The amino acid residue similarities between these lipocalins, indicate putative regions for IgE binding. Comparison with the available, allergen structures from other sources suggests that these allergens are, roughly the same size and that their shape is more spherical than, elliptical.

The three-dimensional structure of the major bovine allergen Bos d 2 has been determined by using x-ray diffraction at 1.8-A resolution. Structurally Bos d 2 is a member of the lipocalin family comprising proteins with transport functions. There is a flat small cavity inside the Bos d 2 protein core suitable for ligand binding, and it is possible that Glu115 and Asn37 inside the core are able to make hydrogen bonds with the ligand. Many allergens from different animals belong to the lipocalin family. The amino acid residue similarities between these lipocalins indicate putative regions for IgE binding. Comparison with the available allergen structures from other sources suggests that these allergens are roughly the same size and that their shape is more spherical than elliptical.

==About this Structure==

1BJ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].

1BJ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].

==Reference==

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[[Category: lipocalin]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:55:53 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1bj7.gif|left|200px]]<br /><applet load="1bj7" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1bj7.gif|left|200px]]<br /><applet load="1bj7" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1bj7, resolution 1.8&Aring;" />
 '''BOVINE LIPOCALIN ALLERGEN BOS D 2'''<br />
 ==Overview==
-The three-dimensional structure of the major bovine allergen Bos d 2 has, been determined by using x-ray diffraction at 1.8-A resolution., Structurally Bos d 2 is a member of the lipocalin family comprising, proteins with transport functions. There is a flat small cavity inside the, Bos d 2 protein core suitable for ligand binding, and it is possible that, Glu115 and Asn37 inside the core are able to make hydrogen bonds with the, ligand. Many allergens from different animals belong to the lipocalin, family. The amino acid residue similarities between these lipocalins, indicate putative regions for IgE binding. Comparison with the available, allergen structures from other sources suggests that these allergens are, roughly the same size and that their shape is more spherical than, elliptical.
+The three-dimensional structure of the major bovine allergen Bos d 2 has been determined by using x-ray diffraction at 1.8-A resolution. Structurally Bos d 2 is a member of the lipocalin family comprising proteins with transport functions. There is a flat small cavity inside the Bos d 2 protein core suitable for ligand binding, and it is possible that Glu115 and Asn37 inside the core are able to make hydrogen bonds with the ligand. Many allergens from different animals belong to the lipocalin family. The amino acid residue similarities between these lipocalins indicate putative regions for IgE binding. Comparison with the available allergen structures from other sources suggests that these allergens are roughly the same size and that their shape is more spherical than elliptical.
 ==About this Structure==
-BJ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].
+BJ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ7 OCA].
 ==Reference==
@@ Line 17: / Line 17: @@
 [[Category: lipocalin]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 11:41:28 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:55:53 2008''