3cgf: Difference between revisions

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[[Image:3cgf.jpg|left|200px]]
{{Seed}}
[[Image:3cgf.png|left|200px]]


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{{STRUCTURE_3cgf|  PDB=3cgf  |  SCENE=  }}  
{{STRUCTURE_3cgf|  PDB=3cgf  |  SCENE=  }}  


'''IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding'''
===IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding===




==Overview==
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A potent IRAK-4 inhibitor was identified through routine project cross screening. The binding mode was inferred using a combination of in silico docking into an IRAK-4 homology model, surrogate crystal structure analysis and chemical analogue SAR.
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==About this Structure==
==About this Structure==
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun  4 09:55:12 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:42:04 2008''
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