User:Boris Brumshtein: Difference between revisions
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====Crystallography==== | ====Crystallography==== | ||
*Protein crystallization utilizing microbatch crystallization, IMPAX I-5, Oryx and Mosquito crystallization robots. | |||
*''Ab initio'' crystallization and crystals optimization. Various crystallization techniques, such as: soaking, co-crystallization, crystallization in presence of heavy metals for phasing, etc. | |||
*Crystal handling and manipulations, micro-manipulations with ZEISS microscope/manipulator system. | |||
*Data acquisition using Rigaku Raxis 4/4++ or synchrotron x-ray sources. | |||
*X-ray data processing software: XDS, HKL2000. | |||
*Protein structure determination using MR, SIR, MIR, MAD, SIRAS approaches with CNS, SHELX and CCP4 software suits. | |||
*Molecular modeling, visualization and analysis software: PyMol, Coot, XtalView, O, CCP4, APBS. | |||
*Docking and small molecule/drug database mining with AutoDock - drug docking and virtual screening, Cambridge Structure Database (CSB), ZINC, ChemOffice. | |||
====Molecular biology and biochemistry==== | ====Molecular biology and biochemistry==== | ||