2r2m: Difference between revisions
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New page: '''Unreleased structure''' The entry 2r2m is ON HOLD Authors: Spurlino, J. Description: 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors ''Page seeded by [http://o... |
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[[Image:2r2m.jpg|left|200px]] | |||
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{{STRUCTURE_2r2m| PDB=2r2m | SCENE= }} | |||
===2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors=== | |||
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{{ABSTRACT_PUBMED_17889527}} | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ==Disease== | ||
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | |||
==About this Structure== | |||
2R2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA]. | |||
==Reference== | |||
2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17889527 17889527] | |||
[[Category: Hirudo medicinalis]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Protein complex]] | |||
[[Category: Thrombin]] | |||
[[Category: Spurlino, J.]] | |||
[[Category: Acute phase]] | |||
[[Category: Blood coagulation]] | |||
[[Category: Calcium]] | |||
[[Category: Cleavage on pair of basic residue]] | |||
[[Category: Disease mutation]] | |||
[[Category: Gamma-carboxyglutamic acid]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Hydrolase]] | |||
[[Category: Kringle]] | |||
[[Category: Polymorphism]] | |||
[[Category: Protease]] | |||
[[Category: Protease inhibitor]] | |||
[[Category: Secreted]] | |||
[[Category: Serine protease]] | |||
[[Category: Serine protease inhibitor]] | |||
[[Category: Sulfation]] | |||
[[Category: Thrombin]] | |||
[[Category: Zymogen]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:08:24 2008'' | |||
